Nuclear Magnetic Resonance (NMR) Imaging Of The Brain: Initial Clinical Experience

G. M. Bydder; R. E. Steiner; I. R. Young; A. S Hall

doi:10.1117/12.933856

29 December 1982 Nuclear Magnetic Resonance (NMR) Imaging Of The Brain: Initial Clinical Experience

G. M. Bydder, R. E. Steiner, I. R. Young, A. S Hall

Proceedings Volume 0347, Application of Optical Instrumentation in Medicine X; (1982) https://doi.org/10.1117/12.933856
Event: Application of Optical Instrumentation in Medicine X, 1982, New Orleans, United States

Abstract

Preliminary results from cranial NMR examinations of 180 patients and 40 volunteers are discussed. Three different pulse sequences have been used to produce images with varying dependence on proton density, T₁ and T₂. Repeated Free Induction Decay (RFID) images which largely reflect proton density are rather featureless and show limited changes in disease. Inversion-recovery (IR) images whose contrast largely depends on differences in T₁ show a high level of grey white matter contrast. In addition acute haemorrhage is associated with shortened values of T but many other conditions such as infarction, infection, demyelination, oedema and thalignancy are associated with increased levels of T₁. Spin-echo (SE) images whose contrast largely depends on differences in T₂ show very little grey white matter contrast but highlight pathological change in a variety of conditions against the bland background of the remaining brain. NMR has a number of important advantages over CT in imaging the brain and appears likely to assume an important role in neurological diagnosis.

Citation Download Citation

G. M. Bydder, R. E. Steiner, I. R. Young, and A. S Hall "Nuclear Magnetic Resonance (NMR) Imaging Of The Brain: Initial Clinical Experience", Proc. SPIE 0347, Application of Optical Instrumentation in Medicine X, (29 December 1982); https://doi.org/10.1117/12.933856

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