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The investigation of specific interactions in biological media requires the development of sensors, combining principles of biochemical recognition and a suitable transduction. In this work a quartz crystal microbalance system was coated with highly ordered lipid films. It was shown that this application can be taken as a model system to study the adsorption behavior of supramolecular structures. To simulate biomimetic structures, we used a combination of `Self Assembling' and `Langmuir-Blodgett' techniques. Glycolipids were incorporated into LB-films as target structures to mimic a native glycocalix.
Maik Liebau,Annegret Hildebrandt,Jens Hartmann,Ulrich Rothe,Johannes Muthing, andReinhard Neubert
"Buildup of Langmuir-Blodgett films on quartz resonators as biomimetic target structures", Proc. SPIE 3539, Chemical Microsensors and Applications, (18 December 1998); https://doi.org/10.1117/12.333748
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Maik Liebau, Annegret Hildebrandt, Jens Hartmann, Ulrich Rothe, Johannes Muthing, Reinhard Neubert, "Buildup of Langmuir-Blodgett films on quartz resonators as biomimetic target structures," Proc. SPIE 3539, Chemical Microsensors and Applications, (18 December 1998); https://doi.org/10.1117/12.333748