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7 August 1998 Functional imaging on human brain activity by continuous light method
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Spectroscopic measurements of the brain activity are discussed in this paper. We introduced a functional near infrared imager which is made of 9 light sources and 4 pairs detectors. Each pair detector has one 850 nm and one 760 nm filtered detector. The light sources are controlled by a computer and the signals from the detectors are filtered, converted and processed by the computer. Functional images of relative changes of blood concentration and deoxygenated hemoglobin in 9 cm by 4 cm detection area are revealed. Since brain function signals afford a contrast due to blood concentration and further oxygenation changes, we focused our studies on brain function by monitoring activity minus rest images.
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Hui Gong, Qingming Luo, Shaoqun Zeng, and Britton Chance "Functional imaging on human brain activity by continuous light method", Proc. SPIE 3548, Biomedical Optics and Lasers: Diagnostics and Treatment, (7 August 1998);

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