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We present a new method for processing confocal fluorescence angiographies in order to extract the topography of the perfused surface. The topographies extracted for various normal and pathologic conditions agree well with morphological and functional conditions. They allow, for example, the quantification of leakage and the verification of treatment success in photodynamic therapy and provide thus a new valuable tool for analyzing the topography of functional pathologies.
Joachim Noack,U. Schmidt-Erfurth,Norbert Koop, andReginald Birngruber
"Functional topographic imaging of the human retina by confocal scanning laser angiography", Proc. SPIE 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II, (4 February 1999); https://doi.org/10.1117/12.339146
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Joachim Noack, U. Schmidt-Erfurth, Norbert Koop, Reginald Birngruber, "Functional topographic imaging of the human retina by confocal scanning laser angiography," Proc. SPIE 3564, Medical Applications of Lasers in Dermatology, Cardiology, Ophthalmology, and Dentistry II, (4 February 1999); https://doi.org/10.1117/12.339146