30 December 1998 Imaging of cutaneous blood vessels using photoacoustic tissue scanning (PATS)
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Abstract
Photoacoustics was used to image optically absorbing structures, like hairs and blood vessels in tissue samples. With 532 nm light depths down to 6 - 9 mm were reached. As the samples we used a 10% solution of Intralipid-10% or real tissue (chicken breast), containing capillaries with blood or a variable dilution of Evans blue. Small PVdF piezoelectric hydrophones were used for detection, in scanning mode for imaging purposes. The depth resolution is about 10 micrometers . The lateral resolution is limited by the diameter of the detector (200 micrometers in our case). This study was undertaken to develop Photoacoustic Tomography of tissue for the localization of blood vessels, e.g. for the detection of blood concentrations (angiogenesis) around tumors.
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Christoph G.A. Hoelen, Christoph G.A. Hoelen, Frits F. M. de Mul, Frits F. M. de Mul, } "Imaging of cutaneous blood vessels using photoacoustic tissue scanning (PATS)", Proc. SPIE 3566, Photon Propagation in Tissues IV, (30 December 1998); doi: 10.1117/12.334361; https://doi.org/10.1117/12.334361
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