22 June 1999 In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer
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Proceedings Volume 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX; (1999) https://doi.org/10.1117/12.351001
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
Temperature increases and the resultant thermal field produced by the irradiation of ex vivo (porcine and human) and in vivo (porcine) tissue models appropriate to the treatment of human breast tissue using Nd:YAG (cw:60W) radiation delivered with an interstitial fiber optic probe were recorded with an array of fifteen 23 gauge needle thermocouple probes connected to a laboratory computer based data acquisition system. Using a stepwise decreasing power cycle to avoid tissue charring, acceptably symmetric thermal fields of repeatable volumetric dimensions were obtained. Reproducible thermal gradients and predictable tissue necrosis without carbonization could be induce din a three centimeter diameter region around the fiber probe during a single treatment lasting only 3 minutes. The time-dependence of the temperature rise of the thermocouples surrounding the LITT probe were quantitatively modeled with simple linear functions during the applied laser heating cycles.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Peter J. Milne, Fabrice Manns, David B. Denham, Jean-Marie A. Parel, and David S. Robinson "In-situ measurement and analysis of the temperature fields in laser interstitial thermotherapy of breast cancer", Proc. SPIE 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, (22 June 1999); doi: 10.1117/12.351001; https://doi.org/10.1117/12.351001
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