22 June 1999 Optical coherence tomography of the rat cochlea: preliminary investigations
Author Affiliations +
Proceedings Volume 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX; (1999) https://doi.org/10.1117/12.350972
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
Optical coherence tomography (OCT) was used to image the internal structure of a rat cochlea. Immediately following sacrifice, the temporal bone of a SPrague-Dawley rat was harvested. Axial OCT cross sectional images (over regions of interest, 1 x 1 mm to 2 x 8 mm) were obtained with a spatial resolution of 10-15 μm. The osseous borders of the lateral membranous labyrinth overlying the cochlea and the scala vestibuli, media, and tympani which were well demarcated by the modiolus, Reissner's and the basilar membranes were clearly identified. OCT can be used to image internal structures in the cochlea without violating the osseous labyrinth, and may potentially be used to diagnose inner ear pathology in vivo in both animal and human subjects.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Brian Jet-Fei Wong, Brian Jet-Fei Wong, Johannes F. de Boer, Johannes F. de Boer, Boris Hyle Park, Boris Hyle Park, Zhongping Chen, Zhongping Chen, J. Stuart Nelson, J. Stuart Nelson, } "Optical coherence tomography of the rat cochlea: preliminary investigations", Proc. SPIE 3590, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems IX, (22 June 1999); doi: 10.1117/12.350972; https://doi.org/10.1117/12.350972
PROCEEDINGS
4 PAGES


SHARE
Back to Top