Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography

Yici Guo; Howard E. Savage; Feng Liu; Stimson P. Schantz M.D.; Peng Pei Ho; Robert R. Alfano

doi:10.1117/12.356846

15 July 1999 Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography

Yici Guo, Howard E. Savage, Feng Liu, Stimson P. Schantz M.D., Peng Pei Ho, Robert R. Alfano

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356846
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

Second harmonic imaging was used to evaluate the subsurface layer structure of hamster cheek pouch mucosal tissues using femtosecond laser technology. Two dimensional images of hamster cheek pouch mucosa were obtained by scanning the second harmonic signal at various lateral and axial positions. The spatial mapping of the second harmonic signals showed depth differentiation between different tissue layers.

Citation Download Citation

Yici Guo, Howard E. Savage, Feng Liu, Stimson P. Schantz M.D., Peng Pei Ho, and Robert R. Alfano "Subsurface structure of tissues investigated by noninvasive optical second harmonic tomography", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356846

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