Tissue oxygenation monitor using NIR spatially resolved spectroscopy

Susumu Suzuki; Sumio Takasaki; Takeo Ozaki; Yukio Kobayashi

doi:10.1117/12.356862

15 July 1999 Tissue oxygenation monitor using NIR spatially resolved spectroscopy

Susumu Suzuki, Sumio Takasaki, Takeo Ozaki, Yukio Kobayashi

Proceedings Volume 3597, Optical Tomography and Spectroscopy of Tissue III; (1999) https://doi.org/10.1117/12.356862
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

A new clinical tissue oxygenation monitor, the NIRO-300, has been developed. In addition to monitoring changes in hemoglobin concentration and redox state of cytochrome oxidase, the instrument can measure a Tissue Oxygenation Index (TOI), which is the ratio of oxygenated to total tissue hemoglobin, by utilizing NIR spatially resolved spectroscopy (SRS). In SRS, the slope of light attenuation versus distance is measured at a distant point from the light input, from which the TOI is calculated using photon diffusion theory. Four laser diodes are used as the light source and Class 1 laser light (IEC 825) is irradiated onto the skin. A high gain and low noise amplifier is used in the detector, which enables a large emitter-detector separations of around 5cm. To evaluate the TOI measured by the NIRO-300, it was compared to the data from a blood gas analyzer (S02 value) in measurements made on phantoms containing intralipid and blood. We also made simultaneous measurements by the NIRO-300 and an NIRS machine based on time resolved spectroscopy (TRS) on human arms. In the both measurements, TOI showed an excellent correlation with the data from blood gas analyzer and the TRS machine, which suggests the efficacy of the TOI data also in clinical use.

Citation Download Citation

Susumu Suzuki, Sumio Takasaki, Takeo Ozaki, and Yukio Kobayashi "Tissue oxygenation monitor using NIR spatially resolved spectroscopy", Proc. SPIE 3597, Optical Tomography and Spectroscopy of Tissue III, (15 July 1999); https://doi.org/10.1117/12.356862

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available