OCT imaging of osteoarthritic cartilage: structure, polarization sensitivity, and clinical feasibility

Xing De Li; Jurgen Herrmann; Ravi K. Ghanta; Constantinos Pitris; Wolfgang Drexler; Christine Jesser; Debra L. Stamper; David Golden; Scott Martin; James G. Fujimoto; Mark E. Brezinski

doi:10.1117/12.347484

30 April 1999 OCT imaging of osteoarthritic cartilage: structure, polarization sensitivity, and clinical feasibility

Xing De Li, Jurgen Herrmann, Ravi K. Ghanta, Constantinos Pitris, Wolfgang Drexler, Christine Jesser, Debra L. Stamper, David Golden, Scott Martin, James G. Fujimoto, Mark E. Brezinski

Author Affiliations +

Proceedings Volume 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III; (1999) https://doi.org/10.1117/12.347484
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

This work demonstrates the feasibility of OCT for identifying early osteoarthritic pathology. In addition to structural abnormalities, changes in collagen fiber organization, an indicator of very early osteoarthritis, were assessed with a polarization sensitive OCT system. A portable, real time, modular OCT system, suitable for both laboratory and clinical settings, has been developed. Preliminary in vivo imaging results obtained during partial knee replacement surgery are discussed.

Citation Download Citation

Xing De Li, Jurgen Herrmann, Ravi K. Ghanta, Constantinos Pitris, Wolfgang Drexler, Christine Jesser, Debra L. Stamper, David Golden, Scott Martin, James G. Fujimoto, and Mark E. Brezinski "OCT imaging of osteoarthritic cartilage: structure, polarization sensitivity, and clinical feasibility", Proc. SPIE 3598, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications III, (30 April 1999); https://doi.org/10.1117/12.347484

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