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17 May 1999 Description of an improved laser Doppler calibrator
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Proceedings Volume 3599, Optical Diagnostics of Biological Fluids IV; (1999) https://doi.org/10.1117/12.348364
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
An improved version of our laser Doppler tester has been developed. The tester contains a tissue phantom made in the form of a thin film. Films with a thickness in the range 20 - 90 micrometer are stacked to reach a total thickness of several millimeters. Motion is realized by rotating discs with a thickness of 20 - 22 micrometer, separated by a static layer of 95 micrometer thickness. The total number of movable layers is 13. The tester contains four phantom stacks, each mimicking a different type of tissue. Since each tissue consists of a stack of thin layers separated by a matching medium, the consequence of a possible mismatch on the photon penetration depth is investigated with the Monte Carlo simulation technique. This leads to a range of refractive indices in which the matching medium must be taken to keep the effect of mismatch below an acceptable level. It appears that for a tissue structure composed of layers with a thickness of 30 micrometer, the refractive index of the matching material should be between 1.50 and 1.54 for a refractive index of the matrix material of the phantom equal to 1.52. Within this range, the effect of mismatch on the probed depth and the total reflection is limited to 2%.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Wiendelt Steenbergen and Frits F. M. de Mul "Description of an improved laser Doppler calibrator", Proc. SPIE 3599, Optical Diagnostics of Biological Fluids IV, (17 May 1999); https://doi.org/10.1117/12.348364
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