14 June 1999 Cavitation thresholds in the rabbit retinal pigmented epithelium
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Proceedings Volume 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical; (1999) https://doi.org/10.1117/12.350019
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
We performed measurements to examine retinal injury from laser pulses in the sub-nanosecond time regime. Both ex-vivo porcine and Dutch belted rabbit retinal pigment epithelium (RPE) models were used in conjunction with time resolved imaging to observe cavitation bubble formation. Included in this study are 3 ps, 300 fs, and 100 fs pulses at a wavelength of 580 nm, as well as 70 ps and 5 ns pulses at 532 nm. Threshold values varied between 37 mJ/cm2 and 50 mJ/cm2 across the range of pulse widths. Following laser irradiation cell viability was checked using a fluorescent dye marker (calcein). Our current results are compared to an earlier investigation using the artificial retina model.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Dale J. Payne, Thomas R. Jost, James J. Elliot, Brent Eilert, Laura Lott, Karen Lott, Gary D. Noojin, Richard A. Hopkins, Charles P. Lin, and Benjamin A. Rockwell "Cavitation thresholds in the rabbit retinal pigmented epithelium", Proc. SPIE 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, (14 June 1999); doi: 10.1117/12.350019; https://doi.org/10.1117/12.350019
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