14 June 1999 Multiple pulse thresholds in live eyes for ultrashort laser pulses in the near infrared
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Proceedings Volume 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical; (1999) https://doi.org/10.1117/12.350009
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States
Abstract
Damage thresholds using multiple laser pulses to produce minimum visible lesions (MVL) in rhesus monkey eyes are reported for near-infrared (800 nm) at 130 femtoseconds. Previous studies by our research group using single pulses in the near-infrared (1060 nm) have determined damage thresholds and retinal spot size dependence. We report the first multiple pulse damage thresholds using femtosecond pulses. MVL thresholds at 1 hour and 24 hours postexposure were determined for 1, 100 and 1,000 pulses and we compare these with other reported multiple pulse thresholds. These new data will be added to the databank for retinal MVL's as a function of pulse repetition rate for this pulsewidth and a comparison will be made with the ANSI standard for multiple pulse exposures. Our measurements show that the retinal ED50 threshold/pulse in the paramacula decreases for increasing number of pulses. The MVL-ED50 at the threshold/pulse decreased by a factor of 4 (0.55 (mu) J to 0.13 (mu) J/pulse) for an increase from 1 to 100 pulses.
© (1999) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
David J. Stolarski, Clarence P. Cain, Cynthia A. Toth, Gary D. Noojin, and Benjamin A. Rockwell "Multiple pulse thresholds in live eyes for ultrashort laser pulses in the near infrared", Proc. SPIE 3601, Laser-Tissue Interaction X: Photochemical, Photothermal, and Photomechanical, (14 June 1999); doi: 10.1117/12.350009; https://doi.org/10.1117/12.350009
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