Hazards and benefits of in-vivo Raman spectroscopy of human skin

Elizabeth A. Carter; Adrian C. Williams; Brian W. Barry; Howell G.M. Edwards

doi:10.1117/12.345390

9 April 1999 Hazards and benefits of in-vivo Raman spectroscopy of human skin

Elizabeth A. Carter, Adrian C. Williams, Brian W. Barry, Howell G.M. Edwards

Proceedings Volume 3608, Biomedical Applications of Raman Spectroscopy; (1999) https://doi.org/10.1117/12.345390
Event: BiOS '99 International Biomedical Optics Symposium, 1999, San Jose, CA, United States

Abstract

The resurgence of Raman spectroscopy, in the late 1980's has led to an increase in the use of the technique for the analysis of biological tissues. Consequently, Raman spectroscopy is now regarded to be a well-established non- invasive, non-destructive technique, which is used to obtain good quality spectra from biological tissues with minimal fluorescence. What is presently of interest to our group is to develop further and establish the technique for in vivo investigations of healthy and diseased skin. This presentation discusses some potentially valuable clinical applications of the technique, and also highlights some of the experimental difficulties that were encountered when examining patients who were receiving treatment for psoriasis.

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Elizabeth A. Carter, Adrian C. Williams, Brian W. Barry, and Howell G.M. Edwards "Hazards and benefits of in-vivo Raman spectroscopy of human skin", Proc. SPIE 3608, Biomedical Applications of Raman Spectroscopy, (9 April 1999); https://doi.org/10.1117/12.345390

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KEYWORDS

Skin

Raman spectroscopy

Tissues

In vitro testing

In vivo imaging

Collagen

Spectroscopy

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