Experimental verification of the advantage of a 256-element ultrasonic phased array for thermal coagulation of deep seated tissue

Douglas R. Daum; Nadine Smith; Nathan McDannold; Kullervo H. Hynynen

doi:10.1117/12.350667

21 June 1999 Experimental verification of the advantage of a 256-element ultrasonic phased array for thermal coagulation of deep seated tissue

Douglas R. Daum, Nadine Smith, Nathan McDannold, Kullervo H. Hynynen

Author Affiliations +

Proceedings Volume 3664, Medical Imaging 1999: Ultrasonic Transducer Engineering; (1999) https://doi.org/10.1117/12.350667
Event: Medical Imaging '99, 1999, San Diego, CA, United States

Abstract

A 256 element ultrasonic phased array was constructed from thermal treatment of deep seated tissue. The 1.1 MHz array had a 10 cm radius of curvature and a 12 cm diameter. The elements formed a planar projection grid of 0.65 X 0.65 cm² such that the focal range of the array was approximately +/- 1 cm from the natural focus of the array both in the focal plane and +/- 2 cm along the array axis. The array was driven with phased continuous wave signals to both shift individual foci and to create multiple focus patterns. The goals of this study were to demonstrate that an array with many elements has the ability to coagulate large volumes of deep seated tissue in a single sonication and to experimentally compare the in vivo thermal measurements of large focal volume sonications to those predicted in a simple simulation model. It was found that the array could coagulate thigh muscle volumes of 3 - 5 cm³ in a twenty second sonication.

Citation Download Citation

Douglas R. Daum, Nadine Smith, Nathan McDannold, and Kullervo H. Hynynen "Experimental verification of the advantage of a 256-element ultrasonic phased array for thermal coagulation of deep seated tissue", Proc. SPIE 3664, Medical Imaging 1999: Ultrasonic Transducer Engineering, (21 June 1999); https://doi.org/10.1117/12.350667

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