The need for more enhanced blood pressure (BP), pulse rate and rhythm senors has given rise to the possibility of using ionic polymer-metal composites (IPMCs) sensors. In this study we propose to use the IPMC sensors to measure systolic and diastolic BP, pulse rate and rhythm. The proposed IPMC sensors take advantage of the endo-ionic mobility within the polymer- metal composite by converting normal and shear load inputs into an induced voltage output across the thickness of the IPMC sensor. The fabricated IPMC sensors are suitable to be installed on the inner surface of a cuff and, therefore, both systolic and diastolic BP, pulse rate, and rhythm can be measured. An added benefit is the ability of measuring 'pulse rhythm' which give a more amplified look at heart irregularities which a typical pulse rate sensor is unable to show. Our data shows IPMC sensors can produce consistent and reliable BP readings, pulse rate, and rhythm. Typically, a linear relationship between applied maximum load and induced maximum voltage was obtained. This result can be easily translated into good BP reading.