25 October 1999 Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline
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Abstract
Alzheimer's Disease is a neurodegenerative disorder marked by progressive cognitive decline. AD presents with many of the same clinical symptoms as senile dementia, but the diagnosis of AD must be confirmed by post-mortem examination of the morphological and histopathological features of the brain. The two classical lesions found in the cortical and hippocampal regions of the brain are the (beta) -amyloid- bearing neuritic plaques and the intraneuronal neurofibrillary tangles.
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Pam S. Bromberg, Kathleen M. Gough, Mandy Ogg, M. R. Del Bigio, Robert Julian, "Synchrotron FTIR microspectroscopy of Alzheimer's diseased brain tissue at the SRC beamline", Proc. SPIE 3775, Accelerator-based Sources of Infrared and Spectroscopic Applications, (25 October 1999); doi: 10.1117/12.366636; https://doi.org/10.1117/12.366636
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