Modeling transport in gas chromatography columns for the Micro-ChemLab

C. Channy Wong; Douglas R. Adkins; Gregory C. Frye-Mason; Mary L. Hudson; Richard J. Kottenstette; Carolyn M. Matzke; John N. Shadid; Andrew G. Salinger

doi:10.1117/12.359329

19 August 1999 Modeling transport in gas chromatography columns for the Micro-ChemLab

C. Channy Wong; Douglas R. Adkins; Gregory C. Frye-Mason; Mary L. Hudson; Richard J. Kottenstette; Carolyn M. Matzke; John N. Shadid; Andrew G. Salinger

Author Affiliations +

Proceedings Volume 3877, Microfluidic Devices and Systems II; (1999) https://doi.org/10.1117/12.359329
Event: Symposium on Micromachining and Microfabrication, 1999, Santa Clara, CA, United States

Abstract

The gas chromatography (GC) column is a critical component in the microsystem for chemical detection ((mu) ChemLab^TM) being developed at Sandia. The goal is to etch a `meter-long' GC column onto a 1-cm² silicon chip while maintaining good chromatographic performance. Our design strategy is to use modeling and simulation approach. We have developed an analytical tool that models the transport and surface interaction process to achieve an optimized design of the GC column. This analytical tool has a flow module and a separation module. The flow module considers both the compressibility and slip flow effects that may significantly influence the gas transport in a long and narrow column. The separation module models analyte transport and physico-chemical interaction with the coated surface in the GC column. It predicts the column efficiency and performance. Results of our analysis will be presented in this paper.

Citation Download Citation

C. Channy Wong, C. Channy Wong, Douglas R. Adkins, Douglas R. Adkins, Gregory C. Frye-Mason, Gregory C. Frye-Mason, Mary L. Hudson, Mary L. Hudson, Richard J. Kottenstette, Richard J. Kottenstette, Carolyn M. Matzke, Carolyn M. Matzke, John N. Shadid, John N. Shadid, Andrew G. Salinger, Andrew G. Salinger, } "Modeling transport in gas chromatography columns for the Micro-ChemLab", Proc. SPIE 3877, Microfluidic Devices and Systems II, (19 August 1999); doi: 10.1117/12.359329; https://doi.org/10.1117/12.359329

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