13 June 2000 Light-scattering model for biological tissue
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Proceedings Volume 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical; (2000) https://doi.org/10.1117/12.388074
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States
Abstract
We suggest that the optical model of a tissue is constructed by different size particles and the corresponding density in a liquid just like some phantoms of tissues. Due to the fact that the nonhomogeneous dimension is about the order of several and hundred micrometers, the Fraunhofer diffraction and process are applicable to biological tissue. We define n(r) as the number of particles per unit volume in tissue with radiuses between r and r + d r, i.e. n(r) is an unnormalized probability density function. We have verified that all of scattering properties of tissue can be obtained as long as the equivalent particle size distribution function n(r) is measured. In particular, the relation between (mu) s and S((theta) ) is dependent on the n(r). The equivalent particle size distribution is feasible for experimental methods and techniques, as well as necessary for scattering principle. Furthermore, the equivalent particle size distribution provide not only a new understanding about the scattering properties of tissue but also a new approach to obtain the scattering coefficient and phase function. In addition, this scheme is helpful to design more precision tissue-simulating phantoms.
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Shusen Xie, Shusen Xie, Hui Li, Hui Li, Lei Lin, Lei Lin, } "Light-scattering model for biological tissue", Proc. SPIE 3914, Laser-Tissue Interaction XI: Photochemical, Photothermal, and Photomechanical, (13 June 2000); doi: 10.1117/12.388074; https://doi.org/10.1117/12.388074
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