Translator Disclaimer
19 May 2000 Monitoring of temperature distribution in tissues with optoacoustic technique in real time
Author Affiliations +
Proceedings Volume 3916, Biomedical Optoacoustics; (2000)
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States
To improve the safety and efficacy of thermal therapy, it is often necessary to map tissue temperature in real time with submillimeter spatial resolution in order to accurately control the boundaries of heated regions and minimize thermal damage to surrounding normal tissues. Current imaging modalities fail to monitor tissue temperature in real time with high resolution and accuracy. We propose to use optoacoustic techniques for accurate, real-time monitoring of tissue temperature with high spatial resolution. Our previous studies demonstrated that the efficiency of optoacoustic wave generation in tissues increases linearly with temperature during uniform heating. In this study, we induced temperature gradients in treated samples and monitor temperature distribution in tissue using optoacoustic technique. Fundamental harmonic of Q-switched Nd:YAG laser was used for optoacoustic wave generation and probing of tissue temperature while the tissue temperature was also monitored with a multisensor temperature probe inserted in the samples. Good agreement between optoacoustic dat and the tissue temperature as recorded via the probe was demonstrated. The optoacoustic techniques was capable of real-time temperature distribution monitoring with submillimeter resolution and high accuracy.
© (2000) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Kirill V. Larin, Irina V. Larina, Massoud Motamedi, and Rinat O. Esenaliev "Monitoring of temperature distribution in tissues with optoacoustic technique in real time", Proc. SPIE 3916, Biomedical Optoacoustics, (19 May 2000);

Back to Top