Application of efficient numerical technique in transport theory for inhomogeneous turbid medium: comparison with experiments

Andrei Dergatchev; Rene Alexander Bolt; Frits F. M. de Mul

doi:10.1117/12.387130

31 May 2000 Application of efficient numerical technique in transport theory for inhomogeneous turbid medium: comparison with experiments

Andrei Dergatchev, Rene Alexander Bolt, Frits F. M. de Mul

Author Affiliations +

Proceedings Volume 3923, Optical Diagnostics of Biological Fluids V; (2000) https://doi.org/10.1117/12.387130
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States

Abstract

In this work we compare experimental results with results of numerical simulations. For our measurements, we used both spatial-resolved and frequency-domain techniques. To describe propagation of photons we solved the rigorous radiative transfer equation (RTE). We found that the Monte- Carlo method (MC) is too time-consuming for large source- detector separations. We achieved flexibility in preparation of experimental medium with tissue-simulating sample containing of several homogeneous layers. Our objective is the investigation of accuracy in determining unknown structures and optical coefficients from measured data, based on the realistic model of the tissue described in the RTE. We have shown that, by comparing the use of the RTE to the diffusion approximation or MC, we achieve better accuracy or universality in source-detector distances.

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Andrei Dergatchev, Rene Alexander Bolt, and Frits F. M. de Mul "Application of efficient numerical technique in transport theory for inhomogeneous turbid medium: comparison with experiments", Proc. SPIE 3923, Optical Diagnostics of Biological Fluids V, (31 May 2000); https://doi.org/10.1117/12.387130

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