26 April 2000 High-throughput pharmocology system HT-PS 100: instrument for automated quantitative analysis of a ligand-receptor interaction based on ligand concentration-dependent functional responses in cells
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Proceedings Volume 3924, Molecular Imaging: Reporters, Dyes, Markers, and Instrumentation; (2000) https://doi.org/10.1117/12.384244
Event: BiOS 2000 The International Symposium on Biomedical Optics, 2000, San Jose, CA, United States
Abstract
Contrary to conventionally used serial discrete dilutions of a ligand to construct concentration-response curves with a few experimental points, we describe here an automated system, HT-PSTM 100, that produces continuous ligand concentration gradients for interrogating cells in flow, and concurrently measures the ligand-induced functional response.
© (2000) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ilya Okun, Ilya Okun, Gregory V. Kaler, Gregory V. Kaler, Michael Otto, Michael Otto, Alex Okun, Alex Okun, } "High-throughput pharmocology system HT-PS 100: instrument for automated quantitative analysis of a ligand-receptor interaction based on ligand concentration-dependent functional responses in cells", Proc. SPIE 3924, Molecular Imaging: Reporters, Dyes, Markers, and Instrumentation, (26 April 2000); doi: 10.1117/12.384244; https://doi.org/10.1117/12.384244
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