6 June 2000 Feature space analysis: effects of MRI protocols
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We present a method for exploring the relationship between the image segmentation results obtained by an optimal feature space method and the MRI protocols used. The steps of the work accomplished are as follows. (1) Three patients with brain tumors were imaged by a 1.5T General Electric Signa MRI System, using multiple protocols (T1- and T2-weighted spin- echo and FLAIR). T1-weighted images were acquired before and after Gadolinium (Gd) injection. (2) Image volumes were co- registered, and images of a slice through the center of the tumor were selected for processing. (3) Nine sets of images were defined by selecting certain MR images (e.g., 4T2's + 1T1, 4T2's + FLAIR, 2T2's + 1T1). (4) Using the images in each set, the optimal feature space was generated and images were segmented into normal tissues and different tumor zones. (5) Segmentation results obtained using different MRI sets were compared. We found that the locations of the clusters for the tumor zones and their corresponding regions in the image domain changed to some extent as a function of the MR images (MRI protocols) used. However, the segmentation results for the total lesion and normal tissues remained almost unchanged.
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Hamid Soltanian-Zadeh, Hamid Soltanian-Zadeh, Lisa Scarpace, Lisa Scarpace, Donald J. Peck, Donald J. Peck, } "Feature space analysis: effects of MRI protocols", Proc. SPIE 3979, Medical Imaging 2000: Image Processing, (6 June 2000); doi: 10.1117/12.387662; https://doi.org/10.1117/12.387662

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