Conformational dynamic of fibrinogen by dielectric spectroscopy

Vladimir P. Berest; Sergiy V. Gatash

doi:10.1117/12.373686

14 December 1999 Conformational dynamic of fibrinogen by dielectric spectroscopy

Vladimir P. Berest, Sergiy V. Gatash

Proceedings Volume 4017, Polymers and Liquid Crystals; (1999) https://doi.org/10.1117/12.373686
Event: International Conference on Dielectric and Related Phenomena '98, 1998, Szczyrk, Poland

Abstract

The information concerning the structural changes of fibrinogen molecule at temperatures form 4 to 52 degrees C has ben obtained by means of dielectric-spectroscopy method. Besides the known conformational transition II, under physiological conditions conformational transition at 20-22 degrees C has been observed in fibrinogen. This transition might be connected with structural transition in peripheral domain of fibrinogen. Revealed conformational transition, probably, determines the character of the temperature dependence of blood platelet aggregation.

Citation Download Citation

Vladimir P. Berest and Sergiy V. Gatash "Conformational dynamic of fibrinogen by dielectric spectroscopy", Proc. SPIE 4017, Polymers and Liquid Crystals, (14 December 1999); https://doi.org/10.1117/12.373686

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