6 July 2000 IR spectroscopy: new results due to fiber optic sensing in view of biomedical application
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Abstract
Optical fibers transparent in the mid-infrared (IR) enable absorption measurements in remote location. New techniques will enhance the possibility using IR fibers for measurements in ATR-mode. If the fiber is in contact with a sample that has characteristic absorption lines, the total transmission of the fiber and sample of these lines will decrease. In this way the absorption of a sample can be determined using a non-destructive method. This work has proven the suitability of flattened IR-Fiber as a tool for detection of organic substances. Initial investigations using bio-organic compounds, bio-liquids, tissue in the native and coagulated state, and micro-organisms have already been carried out with a view to bio-medical usage. An experimental set up was based on an FTIR-spectrometer, fiber optic cables and an external detector. A segment of 1.5 cm at the center of the fiber was flattened to approx. 150 micrometers . Transmission spectra of flattened fibers have been compared to those of the cylindrical fibers. Spectral differences were obtained indicating a possible use for the study of thermal damage in tissues.
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Uwe Bindig, Martina Meinke, Ingo H. Gersonde, Oded Spector, Abraham Katzir, Gerhard J. Mueller, "IR spectroscopy: new results due to fiber optic sensing in view of biomedical application", Proc. SPIE 4129, Subsurface Sensing Technologies and Applications II, (6 July 2000); doi: 10.1117/12.390621; https://doi.org/10.1117/12.390621
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