Efficiency of autofluorescence diagnosis and photodynamic therapy (PDT) of bladder tumors: our own experience

Michal Szygula; Boguslaw Wojciechowski; Aleksander Sieron; Mariusz Adamek; Wojciech Cebula; Tomasz Biniszkiewicz; Witold Zieleznik; Aleksandra Kawczyk-Krupka

doi:10.1117/12.413704

31 January 2001 Efficiency of autofluorescence diagnosis and photodynamic therapy (PDT) of bladder tumors: our own experience

Michal Szygula, Boguslaw Wojciechowski, Aleksander Sieron, Mariusz Adamek, Wojciech Cebula, Tomasz Biniszkiewicz, Witold Zieleznik, Aleksandra Kawczyk-Krupka

Author Affiliations +

Proceedings Volume 4156, Clinical Lasers and Diagnostics; (2001) https://doi.org/10.1117/12.413704
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

The efficiency of autofluorescence diagnosis within urinary bladder was analyzed in the study. We examined two groups of patients: the first one consisting of 22 patients suspected to have bladder cancer and the second one consisting of 45 patients who have undergone transurethral electro resection due to urinary bladder neoplasms. Our goal was to detect cancerous tissue invisible in white-light examination. In the first group sensitivity was 100 percent and specificity was 69.23 percent. In the second group sensitivity was 96 percent and specificity was 80 percent. We also report in the study treatment efficiency of PDT in 12 patients with superficial bladder cancer. In our procedure two hours after the instillation of bladder with ALA solution, the lesion was irradiated by laser light. In 9 out of 12 treated patients regression of bladder tumor was obtained, while in 3 cases a progression of neoplasmatic process was observed.

Citation Download Citation

Michal Szygula, Boguslaw Wojciechowski, Aleksander Sieron, Mariusz Adamek, Wojciech Cebula, Tomasz Biniszkiewicz, Witold Zieleznik, and Aleksandra Kawczyk-Krupka "Efficiency of autofluorescence diagnosis and photodynamic therapy (PDT) of bladder tumors: our own experience", Proc. SPIE 4156, Clinical Lasers and Diagnostics, (31 January 2001); https://doi.org/10.1117/12.413704

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available