19 January 2001 Optical sensor for oxygen tension measurements
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The optical sensor based on the dependence of the phosphorescence lifetime of palladium meso- tetraphenyltetrabenzoporphine on the oxygen concentration was developed. The polystyrene film doped with the dye is deposited on the tip of the fiber wave-guide (d=190 micrometers ) placed in medical needle (d=330 micrometers ). As an excitation source He-Ne laser is used with power 50 mW. The rectangular excitation pulses (pulse durability is of 20 microsecond(s) , durability of fronts- not higher than 1 microsecond(s) , pulse repetition is 0.5-1 Hz) are formed using mechanical obturators and are introduced in wave-guide. The outgoing back from wave-guide phosphorescence radiation is registered using photo detector. The formed electrical signal is processed using computer. The sensor is suitable for invasive oxygen tension measurements. The kinetics of the tumor oxygenation during light irradiation in photodynamic therapy (photosensitizer- sulphonated aluminium phthalocyanine) as well as of the oxygen consumption rate in the catalytic oxidation of sodium ascorbate in the aqueous buffer solution (pH=7.4) in presence of cobalt octacarboxyphthalocyanine as the catalyst are presented.
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Alexander V. Butenin, Alexander V. Butenin, Boris Ya. Kogan, Boris Ya. Kogan, Svetlana N. Dashkevich, Svetlana N. Dashkevich, Oleg L. Kaliya, Oleg L. Kaliya, Eugeny A. Lukyanets, Eugeny A. Lukyanets, N. V. Skuratova, N. V. Skuratova, } "Optical sensor for oxygen tension measurements", Proc. SPIE 4158, Biomonitoring and Endoscopy Technologies, (19 January 2001); doi: 10.1117/12.413787; https://doi.org/10.1117/12.413787

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