3 November 2000 UVA and visible light-induced reactive oxygen species (ROS) formation in cell cultures: an electron paramagnetic resonance (EPR) study
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Abstract
The stimulatory effect of low energy light (LEL) has been attributed to irradiation-induced ROS formation. In the present study we demonstrate that irradiating various cell cultures such as fibroblasts, cardiac and sperm cells with UVA or various light sources in the visible range results in singlet oxygen and OH radical formation. These radicals were monitored by using the EPR technique. We believe that the light induced ROS could mediate previously documented effects of LEL on these cells.
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Rachel Lubart, Rachel Lubart, R. Lavie, R. Lavie, Harry Friedmann, Harry Friedmann, M. Sinyakov, M. Sinyakov, Asher Shainberg, Asher Shainberg, Haim Breitbart, Haim Breitbart, Nili Grossman, Nili Grossman, } "UVA and visible light-induced reactive oxygen species (ROS) formation in cell cultures: an electron paramagnetic resonance (EPR) study", Proc. SPIE 4159, Effects of Low-Power Light on Biological Systems V, (3 November 2000); doi: 10.1117/12.405915; https://doi.org/10.1117/12.405915
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