Determination of the optical properties of breast tissues using frequency-resolved transillumination: basic theory and preliminary results

Jean Yves Le Pommellec; Jean Pierre L'Huillier

doi:10.1117/12.409330

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16 November 2000 Determination of the optical properties of breast tissues using frequency-resolved transillumination: basic theory and preliminary results

Jean Yves Le Pommellec, Jean Pierre L'Huillier

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Proceedings Volume 4161, Optical Biopsy and Tissue Optics; (2000) https://doi.org/10.1117/12.409330
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Breast tissues can be investigated by means of the frequency- resolved spectroscopy, using the transmittance data. A model based on the Fourier transform of the time-resolved transmittance is firstly established, by considering the slightly compressed breast tissues as a finite homogeneous slab of different thicknesses. Two methods of determining the optical properties of this arrangement are presented. The former allows to use moderate modulation frequency of about 100 MHz, while the second requires a limited frequency range of 10 - 20 MHz, in accordance with the low frequency approximation. Under these conditions, computations reveal the potential of extracting the main optical tissue properties from the recorded phase angle shift and modulation linked to transmittance data, at fixed operating modulation frequency. In each case, graphical or numerical solutions can provide good estimates of both reduced scattering and absorption coefficients.

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Jean Yves Le Pommellec and Jean Pierre L'Huillier "Determination of the optical properties of breast tissues using frequency-resolved transillumination: basic theory and preliminary results", Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); https://doi.org/10.1117/12.409330

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