Laser-induced thermotherapy: an in-situ ablation technique for the local treatment of irresectable colorectal liver metastases

Joerg-Peter Ritz; Christoph Martin Isbert; Andre Roggan; Frank Wacker; Heinz-Johannes Buhr; Christoph-Thomas Germer

doi:10.1117/12.409313

16 November 2000 Laser-induced thermotherapy: an in-situ ablation technique for the local treatment of irresectable colorectal liver metastases

Joerg-Peter Ritz, Christoph Martin Isbert, Andre Roggan, Frank Wacker, Heinz-Johannes Buhr, Christoph-Thomas Germer

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Proceedings Volume 4161, Optical Biopsy and Tissue Optics; (2000) https://doi.org/10.1117/12.409313
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

Laser-induced thermotherapy (LITT) is a so called in-situ- ablation technique which is used for the treatment of liver tumors. Coagulation necrosis is induced by transmitting the laser irradiation via quartz fibers directly into the tumor tissue. LITT represents similarly to surgical liver resection a local treatment form for liver metastases. The Nd-YAG laser (1064 nm) was used. The application system was placed percutaneously under open MRI control. On-line monitoring was done with MRI for evaluation of the postoperative follow-up we performed MRI-controls every 3 months. A total of 20 patients were treated. Due to the irradiation plan performed preoperatively, the treated tumors could be completely ablated by hyperthermia in all procedures. Complications were pleural effusion in 7 patients and a bile fistula and subcapsulary liver hematoma in one patient each. Local control of tumor growth can be achieved in tumors having undergone complete hyperthermic ablation. An assessment of the method regarding a prognostic benefit is not yet possible due to the short follow-up period and the small patient population.

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Joerg-Peter Ritz, Christoph Martin Isbert, Andre Roggan, Frank Wacker, Heinz-Johannes Buhr, and Christoph-Thomas Germer "Laser-induced thermotherapy: an in-situ ablation technique for the local treatment of irresectable colorectal liver metastases", Proc. SPIE 4161, Optical Biopsy and Tissue Optics, (16 November 2000); https://doi.org/10.1117/12.409313

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