Sonoluminescence imaging in vivo

Da Xing; Yonghong He; Yonghong Tang; Shici Tan

doi:10.1117/12.405927

3 November 2000 Sonoluminescence imaging in vivo

Da Xing, Yonghong He, Yonghong Tang, Shici Tan

Proceedings Volume 4162, Controlling Tissue Optical Properties: Applications in Clinical Study; (2000) https://doi.org/10.1117/12.405927
Event: EOS/SPIE European Biomedical Optics Week, 2000, Amsterdam, Netherlands

Abstract

In this paper, a sonoluminescence (SL) image of living bodies were obtained with a high-sensitive imaging system for the first time. We found that some kind of chemiluminescent analytic agent, such as FCLA (Fluoresceinyl Cypridina Luminescent Analog) which can work in vivo, could enhance the SL by chemiluminescence through a chemical reaction with oxygen free radicals. In the experiment FCLA is used to enhance the biological SL of mouse body and a clear image of FCLA-enhanced SL was observed in vivo. The biological SL of several typical biological tissues are also investigated. The SL intensity from different tissues has significant difference. With confocal scanning technique, this SL imaging method has potential applications in clinical diagnosis.

Citation Download Citation

Da Xing, Yonghong He, Yonghong Tang, and Shici Tan "Sonoluminescence imaging in vivo", Proc. SPIE 4162, Controlling Tissue Optical Properties: Applications in Clinical Study, (3 November 2000); https://doi.org/10.1117/12.405927

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