18 December 2000 Laser-induced microscopic fluorescence and images of skin tissues
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The microscopic autofluorescence and images of different tissue layer in normal and cancerous skin tissues were studied under a micro spectrophotometric system when using a laser light at 442 nm. The results show that the autofluorescence images of normal skin tissues are much brighter than the cancerous ones, and the autofluorescence intensity from various tissue layers of normal skin is stronger than that of cancerous skin tissues. It is also found that the dermis emits more intense fluorescence while epidermis fluoresces weakly in the skin tissues. The obtained data on the microscopic fluorescence properties in the skin will be useful to aid in the interpretation of underlying mechanisms by which the laser-induced autofluorescence technique differentiates between normal and cancerous skin tissues.
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Zhiwei Huang, Zhiwei Huang, Horn Mun Cheah, Horn Mun Cheah, Teck-Chee Chia, Teck-Chee Chia, Tan Li Ching, Tan Li Ching, } "Laser-induced microscopic fluorescence and images of skin tissues", Proc. SPIE 4164, Laser Microscopy, (18 December 2000); doi: 10.1117/12.410627; https://doi.org/10.1117/12.410627

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