Translator Disclaimer
21 May 2001 ED50 determination of corneal lesions produced by 1318-nm laser radiation pulses
Author Affiliations +
Proceedings Volume 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI; (2001) https://doi.org/10.1117/12.427844
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
High-energy use of 1318 nm laser systems is becoming more prevalent in military and industrial settings. Threshold, ED50, exposure data and mechanism of laser-tissue interaction need to be determined for this wavelength using appropriate animal models that allow for extrapolation to control human exposures. Threshold, ED50, exposure data at 1318 nm for retinal and corneal injury have previously been undertaken and reported for rhesus monkeys. Using comparable methods, we examine exposure data at 1318 nm to determine the ED50 and laser-tissue interaction in the rabbit model to evaluate cornea. We present preliminary data for the ED50 threshold on the cornea from exposure to 1318 nm single laser pulses. Delivery of laser energy is accomplished using an Nd:YAG system producing 1318 nm light in the 0.5 millisecond time exposure regime and in the range of 0 to 500 mJ. Results from this work will aid in the establishment of safety standards for near infrared laser systems.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Bryan K. Ketzenberger, Thomas E. Johnson, Steven P. Wild, Kenneth B. Pletcher, and William P. Roach "ED50 determination of corneal lesions produced by 1318-nm laser radiation pulses", Proc. SPIE 4244, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems XI, (21 May 2001); https://doi.org/10.1117/12.427844
PROCEEDINGS
8 PAGES


SHARE
Advertisement
Advertisement
RELATED CONTENT

Corneal effects produced by IR laser radiation
Proceedings of SPIE (June 30 1990)
Corneal injury to ex vivo eyes exposed to a 3.8...
Proceedings of SPIE (April 24 2005)
Corneal injury from 1318-nm single laser pulses
Proceedings of SPIE (June 26 2002)
Skin exposures from 1318-nm laser pulses
Proceedings of SPIE (July 08 2001)

Back to Top