Performance of amplitude-modified second-order Gaussian filter for the detection of retinal blood vessel

Gang Luo; Opas Chutatape; Sanjay M. Krishnan

doi:10.1117/12.429267

7 June 2001 Performance of amplitude-modified second-order Gaussian filter for the detection of retinal blood vessel

Gang Luo, Opas Chutatape, Sanjay M. Krishnan

Proceedings Volume 4245, Ophthalmic Technologies XI; (2001) https://doi.org/10.1117/12.429267
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Automated analysis of vessel morphology is valuable in diagnosis since it can provide measurable abnormalities in diameter and tortuosity that reflect systemic or local ocular disease. Although the center point of vessel can be easily detected with matched filter, the diameter cannot be obtained from the readily available convolution result in the process of location detection. An amplitude modified second-order Gaussian filter is presented in this paper. Simulation shows that a profile of vessel matches only one amplitude modified second-order Gaussian filter, with which the convolution peak reaches its maximum. Therefore, the width specified parameter of vessel model can be figured out by matching operation with a group of modified Gaussian filters. A vessel diameter measurement concept based on calibration is presented in order to avoid the burden of finding the exact edges of vessels, which has caused several different width definitions for the endless Gaussian curve. The real vessel width can be determined simply according to the relationship built through a calibration procedure in advance after the width specified parameter of Gaussian curve is obtained. Experiments of blood vessel detection of color fundus image are given. The results of the vessel diameter measurement show good agreement with visual inspection.

Citation Download Citation

Gang Luo, Opas Chutatape, and Sanjay M. Krishnan "Performance of amplitude-modified second-order Gaussian filter for the detection of retinal blood vessel", Proc. SPIE 4245, Ophthalmic Technologies XI, (7 June 2001); https://doi.org/10.1117/12.429267

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available