Radio frequency tumor ablation: improving therapeutic efficacy with combined therapies

S. Nahum Goldberg M.D.

doi:10.1117/12.427868

1 June 2001 Radio frequency tumor ablation: improving therapeutic efficacy with combined therapies

S. Nahum Goldberg M.D.

Proceedings Volume 4247, Thermal Treatment of Tissue: Energy Delivery and Assessment; (2001) https://doi.org/10.1117/12.427868
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

Radiofrequency (RF) tumor ablation has been demonstrated as a reliable method for creating thermally induced coagulation necrosis using either a percutaneous approach with image-guidance or direct surgical placement of thin electrodes into tissues to be treated. Early clinical trials with this technology have studied the treatment ofhepatic, cerebral, and bony malignancies. More recently this technology has been used to treat a host of malignant processes throughout the body. However, limitations in the technique and tumor biophysiology prevent optimal treatment of all desired lesions. Hence, investigators are studying combined methods of tumor destruction using RF ablation and adjuvant therapies that can modulate tumor biophysiology. These include using agents to alter tissue conductivity and blood flow, as well as combining RE with chemotherapy. Recent results using the combination therapy approach will be discussed.

Citation Download Citation

S. Nahum Goldberg M.D. "Radio frequency tumor ablation: improving therapeutic efficacy with combined therapies", Proc. SPIE 4247, Thermal Treatment of Tissue: Energy Delivery and Assessment, (1 June 2001); https://doi.org/10.1117/12.427868

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