27 April 2001 Effect of carbon dioxide laser treatment on lesion progression in an intraoral model
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Proceedings Volume 4249, Lasers in Dentistry VII; (2001) https://doi.org/10.1117/12.424499
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
Previous studies have shown that pretreatment of dental enamel by specific carbon dioxide laser conditions inhibited subsequent progression of caries-like lesions in vitro. The aim of the present study was to use an intra-oral model to determine whether similar inhibition is observed in the human mouth. A cross over study with 23 subjects and three regimens was used. Pre-formed varies-like lesions were made in extracted human enamel and exposed intra-orally in partial dentures in each subject to A) placebo dentifrice and no laser treatment, B) placebo dentifrice following laser pretreatment, or C) sodium fluoride dentifrice and no laser treatment during each of three study periods. Samples were assessed by micro radiography to compare the mineral loss before and after each treatment and drive a net change in mineral value. Overall P was not significantly different form L but both P and L were different from F. For those subjects who demineralized in P, L and F were significantly better than P, with L showing an 84 percent inhibition of further demineralization, but no enhancement of demineralization.
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John D. B. Featherstone, John D. B. Featherstone, Daniel Fried, Daniel Fried, Stuart A. Gansky, Stuart A. Gansky, George K. Stookey, George K. Stookey, Ann J. Dunipace, Ann J. Dunipace, } "Effect of carbon dioxide laser treatment on lesion progression in an intraoral model", Proc. SPIE 4249, Lasers in Dentistry VII, (27 April 2001); doi: 10.1117/12.424499; https://doi.org/10.1117/12.424499
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