29 June 2001 Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe
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Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434472
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500 - 590 nm) reflectance with source-detector separations of 0.125 - 0.25 mm and 0.25 - 1.0 mm. For the former case, the major modifications are D equals 1/3(mu) s, and z0 equals 1/(mu) s'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hanli Liu, Maureen Johns, Cole A. Giller, "Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434472; https://doi.org/10.1117/12.434472
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