29 June 2001 Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe
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Proceedings Volume 4250, Optical Tomography and Spectroscopy of Tissue IV; (2001) https://doi.org/10.1117/12.434472
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
Theoretical models available for optical reflectance with small source-detector separations are limited. In this study we reported two modified diffusion models for steady-state, broadband (500 - 590 nm) reflectance with source-detector separations of 0.125 - 0.25 mm and 0.25 - 1.0 mm. For the former case, the major modifications are D equals 1/3(mu) s, and z0 equals 1/(mu) s'; for the latter case, an additional modification is to multiply the separation by a factor of 2. Monte Carlo simulations were used to confirm the modified models at three different hemoglobin concentrations with relative errors of 12% or smaller. These models provide the possibility to extract local optical and physiological parameters of blood-perfused tissues from reflectance data measured with a needle-like probe.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Hanli Liu, Hanli Liu, Maureen Johns, Maureen Johns, Cole A. Giller, Cole A. Giller, "Modified diffusion models for steady-state broadband reflectance with a needlelike optic probe", Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV, (29 June 2001); doi: 10.1117/12.434472; https://doi.org/10.1117/12.434472
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