23 May 2001 Baroreflex regulation measurement using a noninvasive laser Doppler method
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Proceedings Volume 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V; (2001) https://doi.org/10.1117/12.427901
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
In this study, a noninvasive laser Doppler measurement method based on the self-mixing effect of a diode laser was used to measure baroreflex regulation, which is manifest in the blood pressure signal as a 0.1 Hz sinusoidal variation. The laser Doppler measurement system was used to measure the movement of the right radial artery of ten volunteers. Variation in blood pressure caused by the baroreflex affects the elastic properties of the arterial wall. When diastolic blood pressure increases, the elasticity of the arterial wall decreases, causing the wall to lose some of its movability. This decreased elasticity reveals itself in the Doppler signal such that when the blood pressure increases, the Doppler frequency decreases and vice versa. The results show, that the laser Doppler method can be used to measure baroreflex regulation. Finally, baroreflex regulation in the Doppler signal is approximately in the inverse phase with respect to variation in diastolic blood pressure.
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Jukka T. Hast, Risto A. Myllylae, Hannu Sorvoja, Seppo M. Nissilae, "Baroreflex regulation measurement using a noninvasive laser Doppler method", Proc. SPIE 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V, (23 May 2001); doi: 10.1117/12.427901; https://doi.org/10.1117/12.427901
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