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23 May 2001 Modified Monte Carlo of photon transport for studying the imaging properties in highly scattering media
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Proceedings Volume 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V; (2001) https://doi.org/10.1117/12.427900
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
We propose a new method of photon transport to analyze the imaging properties of focused light in highly scattering media. The Monte Carlo based photon transport model is modified to a semi-complete quantum mechanical realization that incorporates probability amplitudes on the path of the unscattered photons. This approach incorporates a phase term on the propagating photons that allows a diffraction- limited analysis on the three-dimensional photon distribution. The interaction between the photons and the lens are treated in the macroscopic level where the lens is considered as a phase transformer that delays the photons by the amount proportional to the thickness of the lens at each embarkation point. When a photon deviates form its original path due to scattering, the probability amplitude of the photon is no longer considered and the intensity of scattered light is calculated similar to the method proposed by Flock. The total intensity is derived by the sum of the unscattered light and the scattered intensity. The 3D point spread functions of objective lenses that are commonly used for microscopic imaging of thick biological samples are presented. Degradation of the 3D PSF is analyzed when the focal plane is at some distance below the surface of th medium with known optical properties.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Vincent Ricardo Daria, Caesar Saloma, and Satoshi Kawata "Modified Monte Carlo of photon transport for studying the imaging properties in highly scattering media", Proc. SPIE 4251, Coherence Domain Optical Methods in Biomedical Science and Clinical Applications V, (23 May 2001); https://doi.org/10.1117/12.427900
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