Comparison of optoacoustic tomography with ultrasound and x-ray imaging for breast cancer detection

Kirill V. Larin; O. Hartrumpf; Irina V. Larina; Rinat O. Esenaliev

doi:10.1117/12.429301

15 June 2001 Comparison of optoacoustic tomography with ultrasound and x-ray imaging for breast cancer detection

Kirill V. Larin, O. Hartrumpf, Irina V. Larina, Rinat O. Esenaliev

Proceedings Volume 4256, Biomedical Optoacoustics II; (2001) https://doi.org/10.1117/12.429301
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

This paper is devoted to comparison new optoacoustic tomography with conventional breast tumors diagnostic techniques such as ultrasonography and X-ray radiography. Experiments were performed in phantoms simulating breast with tumors. The fundamental harmonic of Q-switched Nd:YAG laser (λ = 1064 nm) was used to generate optoacoustic pressure waves. Laser induced pressure waves were detected by a wide-band acoustic transducer. Digital oscilloscope controlled by PC was used to store and process optoacoustic signals. Gelatin phantoms with controlled optical parameters were prepared to simulate breast with tumors. Absorbing volumes colored with naphthol green and hemoglobin were embedded in the gelatin phantoms to model the breast tumors with increased optical absorption. Optoacoustic pressure waves form the phantoms were detected at different angles and 2D images were reconstructed. Comparison of optoacoustic images with images obtained with ultrasound and X-ray techniques proved that optoacoustic method has substantially higher contrast and resolution. Obtained results confirm that laser optoacoustic imaging technique can be an important tool for early breast cancer detection with tumors less than 5 mm in diameter.

Citation Download Citation

Kirill V. Larin, O. Hartrumpf, Irina V. Larina, and Rinat O. Esenaliev "Comparison of optoacoustic tomography with ultrasound and x-ray imaging for breast cancer detection", Proc. SPIE 4256, Biomedical Optoacoustics II, (15 June 2001); https://doi.org/10.1117/12.429301

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available