10 May 2001 Dynamic tether force measurements of the outer hair cells plasma membrane with optical tweezers
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Proceedings Volume 4260, Optical Diagnostics of Living Cells IV; (2001) https://doi.org/10.1117/12.426765
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
The mechanical characteristics of the outer hair cells (OHCs) plasma membrane was studied by forming tethers with optical tweezers. The average force to and from a plasma membrane tether at the lateral wall of the OHC was about 3.5 times greater than that at the basal end of the cell, consistent with the presence of a more extensive cytoskeleton support beneath the PM at the site of the lateral wall. The apparent viscosity of the PM was measured by pulling tethers at different rates while continuously recording the tether force, and was estimated in the range of 13-33 pN*s/micrometers .
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Bahman Anvari, Bahman Anvari, Zhiwei Li, Zhiwei Li, Masayoshi Takashima, Masayoshi Takashima, Peter Brecht, Peter Brecht, Jorge H. Torres, Jorge H. Torres, William E. Brownell, William E. Brownell, } "Dynamic tether force measurements of the outer hair cells plasma membrane with optical tweezers", Proc. SPIE 4260, Optical Diagnostics of Living Cells IV, (10 May 2001); doi: 10.1117/12.426765; https://doi.org/10.1117/12.426765
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