Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins

Galina P. Petrova; Yurii M. Petrusevich; Anastasya N. Evseevicheva; Dmitrii I. Ten

doi:10.1117/12.429334

13 June 2001 Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins

Galina P. Petrova, Yurii M. Petrusevich, Anastasya N. Evseevicheva, Dmitrii I. Ten

Proceedings Volume 4263, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring; (2001) https://doi.org/10.1117/12.429334
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States

Abstract

For the first time, the formation of macromolecular protein clusters in water solutions in the presence of heavy metal ions were observed by the light scattering method. Conditions of the formation and destruction of such clusters were investigated. The clusters mass has a maximum value at the isoelectric point of the protein and increases with the ionic strength of the solution. Formation of clusters in the presence of toxic heavy metals in the blood and living cells is believed to have an essential physiological meaning. The molecular mechanisms of clusters formation based on dipole- dipole interactions of the macromolecules are discussed.

Citation Download Citation

Galina P. Petrova, Yurii M. Petrusevich, Anastasya N. Evseevicheva, and Dmitrii I. Ten "Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins", Proc. SPIE 4263, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring, (13 June 2001); https://doi.org/10.1117/12.429334

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available