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13 June 2001 Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins
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Proceedings Volume 4263, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring; (2001) https://doi.org/10.1117/12.429334
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
For the first time, the formation of macromolecular protein clusters in water solutions in the presence of heavy metal ions were observed by the light scattering method. Conditions of the formation and destruction of such clusters were investigated. The clusters mass has a maximum value at the isoelectric point of the protein and increases with the ionic strength of the solution. Formation of clusters in the presence of toxic heavy metals in the blood and living cells is believed to have an essential physiological meaning. The molecular mechanisms of clusters formation based on dipole- dipole interactions of the macromolecules are discussed.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Galina P. Petrova, Yurii M. Petrusevich, Anastasya N. Evseevicheva, and Dmitrii I. Ten "Optical diagnostics of toxic heavy metal ion's effect on plasma blood proteins", Proc. SPIE 4263, Optical Diagnostics and Sensing of Biological Fluids and Glucose and Cholesterol Monitoring, (13 June 2001); https://doi.org/10.1117/12.429334
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