21 May 2001 Glial cell adhesion and protein adsorption on SAM coated semiconductor and glass surfaces of a microfluidic structure
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Proceedings Volume 4265, Biomedical Instrumentation Based on Micro- and Nanotechnology; (2001) https://doi.org/10.1117/12.427966
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
The development of microsystems that merge biological materials with microfabricated structures is highly dependent on the successful interfacial interactions between these innately incompatible materials. Surface passivation of semiconductor and glass surfaces with thin organic films can attenuate the adhesion of proteins and cells that lead to biofilm formation and biofouling of fluidic structures. We have examined the adhesion of glial cells and serum albumin proteins to microfabricated glass and semiconductor surfaces coated with self-assembled monolayers of octadecyltrimethoxysilane and N-(triethoxysilylpropyl)-O- polyethylene oxide urethane, to evaluate the biocompatibility and surface passivation those coatings provide.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Darryl Y. Sasaki, Darryl Y. Sasaki, Jimmy D. Cox, Jimmy D. Cox, Susan C. Follstaedt, Susan C. Follstaedt, Mark S. Curry, Mark S. Curry, Steven K. Skirboll, Steven K. Skirboll, Paul Lee Gourley, Paul Lee Gourley, "Glial cell adhesion and protein adsorption on SAM coated semiconductor and glass surfaces of a microfluidic structure", Proc. SPIE 4265, Biomedical Instrumentation Based on Micro- and Nanotechnology, (21 May 2001); doi: 10.1117/12.427966; https://doi.org/10.1117/12.427966
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