4 June 2001 Modified confocal scanner system for microarrays
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Proceedings Volume 4266, Microarrays: Optical Technologies and Informatics; (2001); doi: 10.1117/12.427996
Event: BiOS 2001 The International Symposium on Biomedical Optics, 2001, San Jose, CA, United States
Abstract
Based on the original design of the confocal scanner system by Dr. Eisen and his colleagues at Stanford Univ., we have developed a modified confocal scanner system. The modified scanner only used one PMT instead of two PMTs in its precedent one. About half of the dichroic beamsplitters were replaced by reflection mirrors in the modified system. Therefore, we will be able to reduce the power of laser by a fact of 1.5. It will enhance the stability of the laser power and increase the accuracy of the detection system. The size of the modified system was decreased due to the simplified optics system. The optical system and the preliminary scanning results of this modified confocal scanner system will be presented in this paper. We will also discuss some possible further improvement of the system.
© (2001) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Ian C. Hsu, Ray Chen, Yen L. Chen, "Modified confocal scanner system for microarrays", Proc. SPIE 4266, Microarrays: Optical Technologies and Informatics, (4 June 2001); doi: 10.1117/12.427996; https://doi.org/10.1117/12.427996
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KEYWORDS
Scanners

Confocal microscopy

Beam splitters

Mirrors

Luminescence

Laser stabilization

Linear filtering

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