21 May 2001 Ultrasound images of implanted tumors in nude mice using Sono-CT correlated with MRI appearance
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Abstract
Monitoring the effect of novel cancer chemotherapeutic agents in nude mice is now commonly done by external direct measurement and by autopsy. The development of small animal imaging has focused on micro-MRI, micro-CT and micro-PET -- each a highly expensive and highly valuable method. Far less work has been done with ultrasound imaging. We wish to demonstrate a new method of ultrasound imaging of living mice named Sono-CTR, Sono-CTR provides a compound image by combining the images obtained by electronically directing the transducer to scan from multiple angles.
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Matthew T. Freedman, Anita Sarcone, Kathleen F. Pirollo, Chin-Shoou Lin, Esther Chang, "Ultrasound images of implanted tumors in nude mice using Sono-CT correlated with MRI appearance", Proc. SPIE 4321, Medical Imaging 2001: Physiology and Function from Multidimensional Images, (21 May 2001); doi: 10.1117/12.428133; https://doi.org/10.1117/12.428133
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