30 May 2001 C-scan transmission ultrasound based on a hybrid microelectronic sensor array and its physical performance
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A C-scan through-transmission ultrasound system has been constructed based on a patented hybrid microelectronic array that is capable of generating ultrasound images with fluoroscopic presentation. To generate real-time images, ultrasound is introduced into the object under study with a large unfocused plane wave source. The resultant pressure wave strikes the object and is attenuated and scattered. The device detects scattered as well as attenuated ultrasound energy which allows the use of an acoustic lens to focus on detected energy from an object plane. The acoustic lens collects the transmitted energy and focuses it onto the ultrasound sensitive array. The array is made up to two components, a silicon detector/readout array and a piezoelectric material that is deposited onto the array through semiconductor processing. The array is 1 cm on a side consisting of 128x128 pixel elements with 85micrometers pixel spacing. The energy that strikes the piezoelectric material is converted to an analog voltage that is digitized and processed by low cost commercial video electronics. The images generated by the device appear with no speckle artifact with fluoroscopy-like presentation. The images show no obvious geometrical distortion. The experimental results indicated that the system has a spatial resolution of 0.32 mm. It can resolve 3mm objects with low differential contrast and an attenuation coefficient difference less than 0.07 dB/cm/MHz. Phase contrast of the objects are also clearly measurable. A presentation of a C- scan image guided breast biopsy was demonstrated. In addition, punctured needle tracks in a tumor was clearly observed. This implies the potential of observing the spiculation of masses in vivo.
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Shih-Chung Benedict Lo, Shih-Chung Benedict Lo, David Rich, David Rich, Marvin E. Lasser, Marvin E. Lasser, John Kula, John Kula, Hui Zhao, Hui Zhao, Bob Lasser, Bob Lasser, Matthew T. Freedman, Matthew T. Freedman, } "C-scan transmission ultrasound based on a hybrid microelectronic sensor array and its physical performance", Proc. SPIE 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing, (30 May 2001); doi: 10.1117/12.428185; https://doi.org/10.1117/12.428185

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