Feasibility of monitoring HIFU prostate cancer therapy using elastography

Remi Souchon; Jean Yves Chapelon; Michel J. Bertrand; Faouzi Kallel; Jonathan Ophir

doi:10.1117/12.428216

30 May 2001 Feasibility of monitoring HIFU prostate cancer therapy using elastography

Remi Souchon, Jean Yves Chapelon, Michel J. Bertrand, Faouzi Kallel, Jonathan Ophir

Proceedings Volume 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing; (2001) https://doi.org/10.1117/12.428216
Event: Medical Imaging 2001, 2001, San Diego, CA, United States

Abstract

The objective of this study is to investigate the feasibility of elastographic monitoring of High Intensity Focused Ultrasound (HIFU) therapy of prostate cancer. Elastography is an imaging technique based on strain estimation in soft tissues under quasi-static compression. Since pathological tissues and HIFU-induced lesions exhibit different elastic properties than normal tissues, elastography is potentially able to achieve these goals. An ultrasound scanner was connected to a PC to acquire RF images. This setup is compatible with a HIFU device used for prostate cancer therapy by transrectal route. The therapy transducer and the biplane-imaging probe are covered with a balloon filled with a coupling liquid. Compression of the prostate is applied by inflating the balloon, while imaging sector scans of the prostate. In-vivo elastograms of the prostate were acquired before HIFU treatment. Problems inherent to in-vivo acquisitions are reported, such as undesired tangential displacements during the radial compression. This study shows the potential for in-vivo elastogram acquisition of HIFU-induced lesions in the human prostate.

Citation Download Citation

Remi Souchon, Jean Yves Chapelon, Michel J. Bertrand, Faouzi Kallel, and Jonathan Ophir "Feasibility of monitoring HIFU prostate cancer therapy using elastography", Proc. SPIE 4325, Medical Imaging 2001: Ultrasonic Imaging and Signal Processing, (30 May 2001); https://doi.org/10.1117/12.428216

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