Clinical applications of L-lactate oxidase-based biosensor

Keli Xing; Yanfan Liu; Lei Wang; Qiao Han; Lizhi Yin

doi:10.1117/12.440175

14 September 2001 Clinical applications of L-lactate oxidase-based biosensor

Keli Xing, Yanfan Liu, Lei Wang, Qiao Han, Lizhi Yin

Proceedings Volume 4414, International Conference on Sensor Technology (ISTC 2001); (2001) https://doi.org/10.1117/12.440175
Event: International Conference on Sensing units and Sensor Technology, 2001, Wuhan, China

Abstract

A L-lactate oxidase (LOD)-based biosensor is developed for the determination of L-lactate in blood samples. The L- lactate oxidase membrane is prepared by covalently linking LOD into a nylon set, followed by attaching the membrane onto a flow injection type of oxygen electrode. The response of the biosensor is based on the limited diffusion of L- lactate on the L-lactate oxidase membrane. No performance difference have been found between the LOD-based biosensor and regular enzyme optical determination methods for blood sample testing. It is suggested that the LOD-based biosensor may serve as an alternative for the detection of L-lactate in blood.

Citation Download Citation

Keli Xing, Yanfan Liu, Lei Wang, Qiao Han, and Lizhi Yin "Clinical applications of L-lactate oxidase-based biosensor", Proc. SPIE 4414, International Conference on Sensor Technology (ISTC 2001), (14 September 2001); https://doi.org/10.1117/12.440175

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